Schedule for: 24w5292 - Statistical, Computational, Translational, and Ethical Challenges in Biobank Data Analysis
Beginning on Sunday, July 21 and ending Friday July 26, 2024
All times in Banff, Alberta time, MDT (UTC-6).
| Sunday, July 21 | |
|---|---|
| 09:00 - 10:00 | Placeholder (Online) |
| 16:00 - 17:30 | Check-in begins at 16:00 on Sunday and is open 24 hours (Front Desk - Professional Development Centre) |
| 17:30 - 19:30 |
Dinner ↓ A buffet dinner is served daily between 5:30pm and 7:30pm in Vistas Dining Room, top floor of the Sally Borden Building. (Vistas Dining Room) |
| 20:00 - 22:00 | Informal gathering (TCPL Foyer) |
| Monday, July 22 | |
|---|---|
| 07:00 - 08:45 |
Breakfast ↓ Breakfast is served daily between 7 and 9am in the Vistas Dining Room, the top floor of the Sally Borden Building. (Vistas Dining Room) |
| 08:45 - 09:00 |
Introduction and Welcome by BIRS Staff ↓ A brief introduction to BIRS with important logistical information, technology instruction, and opportunity for participants to ask questions. (TCPL 201) |
| 09:00 - 09:30 | Neil Risch: Biobanks from an epidemiologic perspective: experience at Kaiser Permanente (TCPL 201) |
| 09:30 - 10:00 | Lucila Ohno-Machado: Organizing Large Consortium Studies Across Diverse Institutions (TCPL 201) |
| 10:00 - 10:15 | Coffee Break (TCPL Foyer) |
| 10:15 - 10:35 | Hua Xu: Natural language processing for unlocking phenotypic information in clinical notes (TCPL 201) |
| 10:35 - 10:55 | Ruowang Li: Leveraging Biobank-Linked EHR for Genetics Research (TCPL 201) |
| 10:55 - 11:15 | Shefali Verma: Groundwork for Precision Medicine: The Role of Electronic Health Records in Discoveries and Clinical Implementation (TCPL 201) |
| 11:15 - 12:00 | Celia Greenwood: Discussion (Online) |
| 12:00 - 13:30 |
Lunch ↓ Lunch is served daily between 11:30am and 1:30pm in the Vistas Dining Room, the top floor of the Sally Borden Building. (Vistas Dining Room) |
| 14:00 - 14:20 |
Group Photo ↓ Meet in foyer of TCPL to participate in the BIRS group photo. The photograph will be taken outdoors, so dress appropriately for the weather. Please don't be late, or you might not be in the official group photo! (TCPL Foyer) |
| 14:00 - 14:20 | Alicia Martin: All of Us diversity and scale improve polygenic prediction contextually with greatest improvements for under-represented populations (TCPL 201) |
| 14:20 - 14:40 | Eric Gamazon: Statistical Genetics and Genomic Medicine in the Biobank Era: Opportunities and Challenges (TCPL 201) |
| 14:40 - 15:00 | Coffee Break (TCPL Foyer) |
| 15:00 - 15:20 | Can Yang: XMAP: Cross-population fine-mapping by leveraging genetic diversity and accounting for confounding bias (TCPL 201) |
| 15:20 - 15:40 | Andrew Paterson: Everything you always wanted to know about sex chromosomes* (*but were afraid to ask) (TCPL 201) |
| 15:40 - 16:00 | Maryam Zekavat: Connecting ocular and systemic health: Phenome- and genome- wide analyses of retinal layer thicknesses from optical coherence tomography imaging (TCPL 201) |
| 16:00 - 17:00 | Alicia Martin: Discussion (TCPL 201) |
| 17:30 - 19:30 |
Dinner ↓ A buffet dinner is served daily between 5:30pm and 7:30pm in Vistas Dining Room, top floor of the Sally Borden Building. (Vistas Dining Room) |
| Tuesday, July 23 | |
|---|---|
| 07:00 - 08:45 |
Breakfast ↓ Breakfast is served daily between 7 and 9am in the Vistas Dining Room, the top floor of the Sally Borden Building. (Vistas Dining Room) |
| 09:00 - 09:30 | Nilanjan Chatterjee: Integrated Analysis of Biobanks with Summary Statistics (TCPL 201) |
| 09:30 - 10:00 | Peter Kraft: Making epidemiology FAIR: retrofitting legacy studies and building new cohorts (TCPL 201) |
| 10:00 - 10:15 | Coffee Break (TCPL Foyer) |
| 10:15 - 10:35 | Sriram Sankararaman: Scalable mixed models for biobank-scale data: the unreasonable effectiveness of random projections (TCPL 201) |
| 10:35 - 10:55 | Josee Dupuis: Novel Approaches to Exploit Family History in Genetic Association Tests, with Applications to the UK Biobank (Online) |
| 10:55 - 11:15 | Iuliana Ionita-Laza: Quantile Regression for biomarkers in the UK Biobank (TCPL 201) |
| 11:15 - 12:00 | Peter Kraft: Discussion (TCPL 201) |
| 12:00 - 13:30 |
Lunch ↓ Lunch is served daily between 11:30am and 1:30pm in the Vistas Dining Room, the top floor of the Sally Borden Building. (Vistas Dining Room) |
| 13:45 - 14:05 | Xiang Zhou: VINTAGE: A unified framework integrating gene expression mapping studies with genome-wide association studies for detecting and deciphering gene-trait associations (TCPL 201) |
| 14:05 - 14:25 | Dajiang Liu: Integrating single cell eQTLs to dissect risk genes for immune mediated diseases (TCPL 201) |
| 14:25 - 14:45 | Gao Wang: Elucidating Genetic Etiology of Complex Disease through Population-Scale Functional Genomic Studies (TCPL 201) |
| 14:45 - 15:00 | Coffee Break (TCPL Foyer) |
| 15:00 - 15:20 | Hae Kyung Im: Error in prediction does not inflate type I error in TWAS but polygenicity does (TCPL 201) |
| 15:20 - 15:40 | Wei Pan: Enhancing non-linear TWAS/PWAS via trait imputation with applications to Alzheimer's disease (TCPL 201) |
| 15:40 - 16:00 | Jingjing Yang: SR-TWAS: Leveraging Multiple Reference Panels to Improve TWAS Power by Ensemble Machine Learning (TCPL 201) |
| 16:00 - 17:00 | Xiang Zhou: Discussion (TCPL 201) |
| 17:30 - 19:30 |
Dinner ↓ A buffet dinner is served daily between 5:30pm and 7:30pm in Vistas Dining Room, top floor of the Sally Borden Building. (Vistas Dining Room) |
| Wednesday, July 24 | |
|---|---|
| 07:00 - 08:45 |
Breakfast ↓ Breakfast is served daily between 7 and 9am in the Vistas Dining Room, the top floor of the Sally Borden Building. (Vistas Dining Room) |
| 09:00 - 09:20 | Jian Yang: Genetics and clinical implications of somatic mutational burden in normal blood (Online) |
| 09:20 - 09:40 | Hongtu Zhu: Multi-Disease Prediction and Individual Risk Assessment Based on UK Biobank Data (Online) |
| 09:40 - 10:00 | Xihao Li: Statistical and computational considerations for integrative analysis of biobank whole genome sequencing studies (Online) |
| 10:00 - 10:15 | Coffee Break (TCPL Foyer) |
| 10:15 - 10:35 | Daphne Marschenko: Ethical Implications of Biobank Analysis: From humans, to data, and back again (Online) |
| 10:35 - 10:55 | Anna Lewis: Data governance strategies for minimizing risks from reidentification and group harms (TCPL 201) |
| 10:55 - 11:15 | Fan Wang: Computationally Efficient Approaches for Whole-Genome Quantile Inference with Related Samples (TCPL 201) |
| 11:15 - 12:00 | Hongyu Zhao: Discussion (TCPL 201) |
| 12:00 - 13:30 |
Lunch ↓ Lunch is served daily between 11:30am and 1:30pm in the Vistas Dining Room, the top floor of the Sally Borden Building. (Vistas Dining Room) |
| 13:30 - 17:30 | Free Afternoon (Banff National Park) |
| 17:30 - 19:30 |
Dinner ↓ A buffet dinner is served daily between 5:30pm and 7:30pm in Vistas Dining Room, top floor of the Sally Borden Building. (Vistas Dining Room) |
| Thursday, July 25 | |
|---|---|
| 07:00 - 08:45 |
Breakfast ↓ Breakfast is served daily between 7 and 9am in the Vistas Dining Room, the top floor of the Sally Borden Building. (Vistas Dining Room) |
| 09:00 - 09:20 | Frank Dudbridge: GWAS and Mendelian randomisation of disease progression traits (Online) |
| 09:20 - 09:40 | Qingyuan Zhao: Some recent progress in Mendelian randomization (Online) |
| 09:40 - 10:00 | Xiaofeng Zhu: Uncovering Gene-Environment Interactions through Mendelian Randomization (TCPL 201) |
| 10:00 - 10:15 | Coffee Break (TCPL Foyer) |
| 10:15 - 10:35 | Tianyuan Lu: Challenges in causal interpretation of Mendelian Randomization with large biobank data (TCPL 201) |
| 10:35 - 10:55 | Quan Long: A statistical method for image-mediated association studies discovers genes and pathways associated with four brain disorders (TCPL 201) |
| 10:55 - 11:15 | Dehan Kong: Fighting Noise with Noise: Mendelian Randomization Studies with Pseudo Variables (TCPL 201) |
| 11:15 - 12:00 | Neil Risch: Discussion (TCPL 201) |
| 12:00 - 13:30 |
Lunch ↓ Lunch is served daily between 11:30am and 1:30pm in the Vistas Dining Room, the top floor of the Sally Borden Building. (Vistas Dining Room) |
| 13:45 - 14:05 | Jean Yee Hwa Yang: Exploring genomic influence on in-silico spatial gene expression data (TCPL 201) |
| 14:05 - 14:25 | Lorin Crawford: Discovering non-additive heritability using additive GWAS summary statistics (TCPL 201) |
| 14:25 - 14:45 | Wenmin Zhang: Improving understanding of complex trait genetics with probabilistic graphical models and variational inference (TCPL 201) |
| 14:45 - 15:00 | Coffee Break (TCPL Foyer) |
| 15:00 - 15:20 | Charles Kooperberg: Evaluating the performance of Polygenic Risk Scores in Diverse Populations (TCPL 201) |
| 15:20 - 15:40 | Yun Li: Improving polygenic risk prediction in admixed populations by explicitly modeling ancestral-differential effects via GAUDI (TCPL 201) |
| 15:40 - 16:00 | Li Hsu: Leveraging biobank data for set-based association analysis with genetically predicted traits (TCPL 201) |
| 16:00 - 17:00 | Lorin Crawford: Discussion (TCPL 201) |
| 17:30 - 19:30 |
Dinner ↓ A buffet dinner is served daily between 5:30pm and 7:30pm in Vistas Dining Room, top floor of the Sally Borden Building. (Vistas Dining Room) |
| Friday, July 26 | |
|---|---|
| 07:00 - 08:45 |
Breakfast ↓ Breakfast is served daily between 7 and 9am in the Vistas Dining Room, the top floor of the Sally Borden Building. (Vistas Dining Room) |
| 09:00 - 09:20 | Charles Dupras: How to assess risks to privacy and confidentiality in multi-omic research and databases (Online) |
| 09:20 - 09:40 | Qingrun Zhang: Stabilized COre gene and Pathway Election uncovers pan-cancer shared pathways and a cancer-specific driver (TCPL 201) |
| 10:00 - 10:15 | Coffee Break (TCPL Foyer) |
| 10:30 - 11:00 |
Checkout by 11AM ↓ 5-day workshop participants are welcome to use BIRS facilities (TCPL ) until 3 pm on Friday, although participants are still required to checkout of the guest rooms by 11AM. (Front Desk - Professional Development Centre) |
| 12:00 - 13:30 | Lunch from 11:30 to 13:30 (Vistas Dining Room) |
