Schedule for: 18w5045 - Rules of Protein-DNA Recognition: Computational and Experimental Advances
Beginning on Sunday, June 3 and ending Friday June 8, 2018
All times in Oaxaca, Mexico time, CDT (UTC-5).
| Sunday, June 3 | |
|---|---|
| 14:00 - 23:59 | Check-in begins (Front desk at your assigned hotel) |
| 19:30 - 22:00 | Dinner (Restaurant Hotel Hacienda Los Laureles) |
| 20:30 - 21:30 | Informal gathering (Hotel Hacienda Los Laureles) |
| Monday, June 4 | |
|---|---|
| 07:30 - 08:45 | Breakfast (Restaurant at your assigned hotel) |
| 09:00 - 09:15 | Introduction and Welcome (Conference Room San Felipe) |
| 09:15 - 10:15 | Gary Stormo: The Coming of the Golden Age (Conference Room San Felipe) |
| 10:15 - 10:45 | Coffee Break (Conference Room San Felipe) |
| 11:00 - 11:30 | Richard Mann (Conference Room San Felipe) |
| 11:30 - 12:00 | Juan Fuxman Bass: Gene regulatory network rewiring by disease variants and transcription factor isoforms (Conference Room San Felipe) |
| 12:00 - 12:30 | Raluca Gordan: New insights into protein-DNA recognition: binding specificity to mispaired DNA, and divergence in specificity within TF families (Conference Room San Felipe) |
| 12:30 - 13:00 | Mona Singh: Perturbed DNA binding and disease (Conference Room San Felipe) |
| 13:20 - 13:30 | Group Photo (Hotel Hacienda Los Laureles) |
| 13:30 - 15:00 | Lunch (Restaurant Hotel Hacienda Los Laureles) |
| 15:00 - 15:30 | Eric Ortlund: Distal substitutions alter conformational space to create new functions among paralogous transcription factors (Conference Room San Felipe) |
| 15:30 - 16:00 | Trevor Siggers: Biophysical principles of PU.1 binding revealed by nextPBM (Conference Room San Felipe) |
| 16:00 - 16:30 | Coffee Break (Conference Room San Felipe) |
| 16:30 - 17:00 | Alejandra Eugenia Medina Rivera: Inter-tissue, interspecies comparisons of the transcription factor JUN in endothelial cells identify regulatory mechanisms associated with vascular disease (Conference Room San Felipe) |
| 17:00 - 17:30 | Yael Mandel-Gutfreund: Revealing the role of dual DNA and RNA binding proteins in Human embryonic stem cells (Conference Room San Felipe) |
| 17:30 - 18:00 | Marcus Noyes: Direct and indirect influences that adjacent C2H2 zinc fingers have on DNA-binding strategies (Conference Room San Felipe) |
| 19:00 - 21:00 | Dinner (Restaurant Hotel Hacienda Los Laureles) |
| Tuesday, June 5 | |
|---|---|
| 07:30 - 09:00 | Breakfast (Restaurant at your assigned hotel) |
| 09:10 - 09:30 | Julia Rogers: Novel mechanism of bispecificity in forkhead transcription factors (Conference Room San Felipe) |
| 09:30 - 10:00 | Alexandre Morozov: Higher-order chromatin structure: The role of Mediator (Conference Room San Felipe) |
| 10:00 - 10:20 | Chaitanya Rastogi: Accurate and sensitive quantification of protein-DNA binding affinity (Conference Room San Felipe) |
| 10:30 - 11:00 | Coffee Break (Conference Room San Felipe) |
| 11:00 - 11:20 | Víctor H. Tierrafría: Microbial Conditions Ontology (MCO): an effort to standardize the annotation of experimental conditions in microbial data (Conference Room San Felipe) |
| 11:20 - 11:50 | Barak Cohen: Integration of local and regional cis-regulatory information (Conference Room San Felipe) |
| 11:50 - 12:20 | Joe Thornton: Mechanisms for the evolution of steroid receptor/DNA specificity using ancestral reconstruction and deep mutational scanning (Conference Room San Felipe) |
| 12:20 - 12:50 | Aseem Ansari: Designing sequence-specific DNA binding drugs (Conference Room San Felipe) |
| 12:50 - 13:30 | OPEN (Conference Room San Felipe) |
| 13:30 - 15:00 | Lunch (Restaurant Hotel Hacienda Los Laureles) |
| 15:00 - 15:30 | Julio Collado-Vides: A global analysis of the distance to transcription initiation of binding sites in bacterial promoters (Conference Room San Felipe) |
| 15:30 - 16:00 | Polly Fordyce: Probing effects of flanking sequence via high-resolution measurements of millions of TF-DNA binding energies (Conference Room San Felipe) |
| 16:00 - 16:30 | Coffee Break (Conference Room San Felipe) |
| 16:30 - 17:00 | Matthew Weirauch: Transcription factors operate across disease loci, with EBNA2 implicated in autoimmunity (Conference Room San Felipe) |
| 17:00 - 17:30 | Manuel Llinas: Transcription factor crosstalk during developmental differentiation (Conference Room San Felipe) |
| 17:30 - 18:00 | Kai Chen: Transcriptional atlas of a proto-vertebrate (Conference Room San Felipe) |
| 19:00 - 21:00 | Dinner (Restaurant Hotel Hacienda Los Laureles) |
| Wednesday, June 6 | |
|---|---|
| 07:30 - 09:00 | Breakfast (Restaurant at your assigned hotel) |
| 09:00 - 09:30 | Jussi Taipale: Genome-wide analysis of protein-DNA interactions (Conference Room San Felipe) |
| 09:30 - 10:00 | Bart Deplancke: SMILE-seq-based analysis of DNA binding specificities of human KRAB zinc-finger proteins (Conference Room San Felipe) |
| 10:00 - 10:20 | April Mueller: A protein-protein interaction of adjacent C2H2 zinc fingers controls binding geometry and the residues able to specify DNA targets (Conference Room San Felipe) |
| 10:30 - 11:00 | Coffee Break (Conference Room San Felipe) |
| 11:00 - 11:20 | Ignacio Ibarra Del Río: Expanding the prediction of protein-DNA ternary complex binding using DNA-shape (Conference Room San Felipe) |
| 11:20 - 11:40 | Jeffrey Spencer: A deep mutational scan of Cas9 reveals that mutations in the PI domain influence targeting fidelity (Conference Room San Felipe) |
| 11:40 - 12:10 | Tim Hughes: The Human Transcription Factors (Conference Room San Felipe) |
| 12:30 - 13:30 | Lunch (Restaurant Hotel Hacienda Los Laureles) |
| 13:30 - 19:00 | Free Afternoon (Oaxaca) |
| 19:00 - 21:00 | Dinner (Restaurant Hotel Hacienda Los Laureles) |
| Thursday, June 7 | |
|---|---|
| 07:30 - 09:00 | Breakfast (Restaurant at your assigned hotel) |
| 09:00 - 09:30 | Harmen J. Bussemaker: A unified approach for quantifying and interpreting DNA shape readout by transcription factors (Conference Room San Felipe) |
| 09:30 - 10:00 | Miles Pufall: The effects of sequence and mismatches on Cas9 activity (Conference Room San Felipe) |
| 10:00 - 10:30 | Yaakov Levy: Molecular principles for optimizing protein-DNA interactions (Conference Room San Felipe) |
| 10:30 - 11:00 | Coffee Break (Conference Room San Felipe) |
| 11:00 - 11:30 | Remo Rohs: A tale of DNA shape analysis: a user manual and next steps (Conference Room San Felipe) |
| 11:30 - 12:00 | Tom Tullius: DNA shape – intrinsic or induced? (Conference Room San Felipe) |
| 12:00 - 12:30 | Charles Vinson: Modified cytosine and DNA binding (Conference Room San Felipe) |
| 12:50 - 13:30 | OPEN (Conference Room San Felipe) |
| 13:30 - 15:00 | Lunch (Restaurant Hotel Hacienda Los Laureles) |
| 15:00 - 15:30 | Henry Pratt: The ENCODE Encyclopedia of candidate cis-regulatory elements and transcription factor binding sites (Conference Room San Felipe) |
| 15:30 - 16:00 | Jose Rodriguez-Martinez: Combinatorial recognition of DNA by bZIP transcription factors (Conference Room San Felipe) |
| 16:00 - 16:30 | Coffee Break (Conference Room San Felipe) |
| 16:30 - 17:00 | Yaron Orenstein: Deep learning for protein-RNA interactions (Conference Room San Felipe) |
| 17:00 - 17:30 | Carlos Camacho: Towards a zinc finger code for RNA recognition (Conference Room San Felipe) |
| 17:30 - 18:00 | Jeff Vierstra: Footprinting the human genome (Conference Room San Felipe) |
| 19:00 - 21:00 | Dinner (Restaurant Hotel Hacienda Los Laureles) |
| Friday, June 8 | |
|---|---|
| 07:30 - 09:00 | Breakfast (Restaurant at your assigned hotel) |
| 10:30 - 11:00 | Coffee Break (Conference Room San Felipe) |
| 12:00 - 14:00 | Lunch (Restaurant Hotel Hacienda Los Laureles) |
